Exploring Benefits of Serum-derived Bovine Immunoglobulin

Serum-derived Bovine Immunoglobulin (SBI) is a well-tolerated medical food researched to help optimize the gastrointestinal inflammatory response and improve balance in the gut microbiome. SBI is commonly recommended for people dealing with chronic gut lining irritation and its related issues—from nutrient malabsorption and bowel irregularities to increased intestinal permeability (leaky gut syndrome) and its downstream … Continue reading Exploring Benefits of Serum-derived Bovine Immunoglobulin

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part X

More on insulin metabolism plus some final "big picture" thoughts on what is creating this epidemic of cns inflammation and insulin resistance In concluding this review of the impact of suboptimal insulin and glucose metabolism on the brain and its tendency to lead to the development of amyloid beta (Aβ) and other adverse changes consistent … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part X

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part IX

More research on Senile Dementia/Alzheimer's disease and its connection with dysinsulinism In part VIII of this series I began my discussion on how disturbances in insulin metabolism can alter brain chemistry, leading to formation of the generally recognized cause of Alzheimer's disease/senile dementia, amyloid beta (Aβ), commonly known as "amyloid plaques."  Furthermore, I pointed out … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part IX

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VIII

Senile Dementia/Alzheimer's Disease and its Connection with Dysinsulinism By now I hope I have convinced those of you who have been reading this entire series that chronic inflammation plays a major role in the development and continuing loss of neurologic function in all neurodegenerative diseases, including senile dementia/Alzheimer's disease.  However, given the vicious circle relationship … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VIII

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VII

Depression - Its Connection with Chronic Inflammation, Vitamin B6 Depletion, Disturbances in Kynurenine Metabolism and Diabetes In part VI of this series I ended with a discussion of the hypothesis by Oxenkrug (1, 2) that, when chronic inflammation combines with vitamin B6 deficiency, disturbances in kynurenine metabolism can ensue which can not only contribute to depression … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VII

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VI

DEPRESSION - DOES RESEARCH THAT DOWNPLAYS THE KYNURENINE PATHWAY CONNECTION IN FACT REFLECT SUBOPTIMAL NUTRIENT STATUS? Much of part V of this series focused on research which provided strong support for the hypothesis that chronic inflammation creates depression via alterations in tryptophan metabolism that redirect tryptophan away from serotonin and melatonin production and towards the … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part VI

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part V

DEPRESSION - MORE INFORMATION TO SUPPORT THE IDEA THAT IT IS TRULY AN INFLAMMATORY ILLNESS As you might imagine, despite the large volume of research supporting the idea that depression is an inflammatory illness, many in both the clinical and academic communities will point to various manifestations and subtleties of the average case of depression … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review of the Evidence – Part V

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part IV

 DEPRESSION - IS IT TRULY AN INFLAMMATORY ILLNESS? Of all the behavioral and neurodegenerative disorders considered so far in this series, there is no question that, from a clinical standpoint, the one that seems to be most prevalent and, judging from the use of SSRIs in this country, generating the most concern, is depression.  Of … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part IV

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part III

THE COMPLICATED RELATIONSHIP BETWEEN ANTIDEPRESSANT MEDICATION AND INFLAMMATION Assuming that inflammation plays an important role in all neurodegenerative and mood disorders, as I suggested in the first two installments of this series, another important question must now be asked: Even though efficacy of antidepressant medication is highly variable with depression, when it is effective could the reason … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part III

Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part II

In part I of this series I reviewed the paper "Immune aging, dysmetabolism, and inflammation in neurological diseases" by Deleidi et al (1) in which it was stated that the key cell in the CNS that appears to be most responsible for much of the damage seen in the CNS as the result of chronic … Continue reading Are Chronic Inflammation and its Metabolic Counterpart, Insulin Resistance, the Common Denominators for All Chronic Behavioral and Neurodegenerative Disorders? – A Review Of the Evidence – Part II